Publications

The within-individual reproducibility of the disease severity index from the HepQuant SHUNT test of liver function and physiology

Burton, James R. et al. | Transl Res. 2021 Jul;233:5-15

Cost-Effectiveness of an Oral Cholate Challenge Test for the Management of Patients at Risk for Large Esophageal Varices

Shailesh Chavan, Michael P. McRae, Kelly R. Pitts, Gregory T. Everson | Research Article | published 22 November 2024 PLOS ONE

Cholate Shunt, Oral Cholate Challenge and Endoscopic Lesions of Portal Hypertension: The SHUNT-V Study.

Mitchell Shiffman, K. Rajender Reddy, Michael, D. Leise3, Kamran Qureshi, Alastair D. Smith, Steve Helmke, John Kittelson, Michael P. McRae, Joanne C. Imperial, Gregory T. Everson, the SHUNT-V Investigators | Alimentary Pharmacology & Therapeutics, 2024; 0:1–13

A Validated LC-MS/MS Assay for the Quantitation of Cholate Isotopes in Human Serum

Steve M. Helmke, Michael P. McRae, Uwe Christians, Touraj Shokati, Gregory T. Everson | The Journal of Applied Laboratory Medicine 2024 Aug 16

The Oral Cholate Challenge Test Quantifies Risk for Liver-Related Clinical Outcomes in Primary Sclerosing Cholangitis

Steve Helmke, John Kittelson, Joanne Imperial, Michael McRae, Gregory T. Everson | Gastro Hep Advances 2024

Editorial: Reading the cholate—A new gateway to portal hypertension and oesophageal varices: Authors’ reply

Tarek Hassanein, Andrew P. Keaveny, Parvez Mantry, Alastair D. Smith, Michael P. McRae, John Kittelson, Steve Helmke, Gregory T. Everson, for the SHUNT-V Investigators | Aliment Pharmacol Ther 2024

Hepatic improvement within 27 days of avenciguat treatment in Child-Pugh A cirrhosis detected by an oral cholate challenge test

Eric J. Lawitz, Judith Ertle, Corinna Schoelch, Isabella Gashaw, Steve M. Helmke, Gregory T Everson | Liver Transplantation 2024 Jun 12

Liver Function and Portal-Systemic Shunting Quantified by the Oral Cholate Challenge Test and Risk for Large Esophageal Varices

Tarek Hassanein, Andrew P. Keaveny, Parvez Mantry, Alastair D. Smith, Michael P. McRae, John Kittelson, Steve Helmke, Gregory T. Everson for the SHUNT-V Investigators | Aliment Pharmacol Ther 2024 May 22

Hepatic Dysfunction Quantified by HepQuant DuO Outperforms Child-Pugh Classification in Predicting the Pharmacokinetics of Ampreloxetine

Jitendra Kanodia, Hugh Giovinazzo, Wayne Yates, David L. Bourdet, Steve M. Helmke, and Gregory T. Everson | Clin Pharmacol Ther 2024 Apr 23

Within Individual Reproducibility of a Dual Sample Oral Cholate Challenge Test (DuO) and Simplified Versions of the HepQuant SHUNT Test

Michael P. McRae, John Kittelson, Steve M. Helmke, and Gregory T. Everson | Clin Translational Sci 2024