Publications

March 2025

Rencofilstat Treatment Improves Liver Function in MASH With Advanced Fibrosis as Quantified by HepQuant DuO

Stephen A. Harrison, Patrick Mayo, Todd Hobbs, Caroline Zhao, Carlos Canizares, Robert Foster, Michael P. McRae, Steve M. Helmke, Gregory T. Everson | Liver International | 01 March 2025

November 2024

Measuring the Risk of Clinical Events (RISK ACE) by Quantifying Liver Function: A Patient-Centric Model

John Kittelson, Michael P. McRae, Gregory T. Everson | European Journal of Internal Medicine 2024; 132:160-163 | 29 November 2024

Safety and pharmacokinetics of BI 685509, a soluble guanylyl cyclase activator, in patients with cirrhosis: A randomized Phase Ib study

Eric J. Lawitz, Thomas Reiberger, Jörn M. Schattenberg, Corinna Schoelch, Harvey O. Coxson, Diane Wong, Judith Ertle | Hepatology Communications. 2023 Mar 0;7:e0276

Alterations in Liver Perfusion in Adults with Fontan Circulation as Assessed by Dual Cholate Clearance

Yuli Y. Kim, Annique Nyman, Yuan-Shung Huang, Alexis Z. Tomlinson, Michael P. McRae, Greg T. Everson, Sumeet Vaikunth, Benjamin Rosenthal, Jack Rychik, Maarouf A. Hoteit | Journal of the American Heart Association | 2025 | March 2025

Cost-Effectiveness of an Oral Cholate Challenge Test for the Management of Patients at Risk for Large Esophageal Varices

Shailesh Chavan, Michael P. McRae, Kelly R. Pitts, Gregory T. Everson | Research Article | published 22 November 2024 PLOS ONE

Cholate Shunt, Oral Cholate Challenge and Endoscopic Lesions of Portal Hypertension: The SHUNT-V Study.

Mitchell Shiffman, K. Rajender Reddy, Michael, D. Leise3, Kamran Qureshi, Alastair D. Smith, Steve Helmke, John Kittelson, Michael P. McRae, Joanne C. Imperial, Gregory T. Everson, the SHUNT-V Investigators | Alimentary Pharmacology & Therapeutics, 2024; 61: 75-87

A Validated LC-MS/MS Assay for the Quantitation of Cholate Isotopes in Human Serum

Steve M. Helmke, Michael P. McRae, Uwe Christians, Touraj Shokati, Gregory T. Everson | The Journal of Applied Laboratory Medicine 2024 Aug 16

The Oral Cholate Challenge Test Quantifies Risk for Liver-Related Clinical Outcomes in Primary Sclerosing Cholangitis

Steve Helmke, John Kittelson, Joanne Imperial, Michael McRae, Gregory T. Everson | Gastro Hep Advances 2024

Editorial: Reading the cholate—A new gateway to portal hypertension and oesophageal varices: Authors’ reply

Tarek Hassanein, Andrew P. Keaveny, Parvez Mantry, Alastair D. Smith, Michael P. McRae, John Kittelson, Steve Helmke, Gregory T. Everson, for the SHUNT-V Investigators | Aliment Pharmacol Ther 2024

Hepatic improvement within 27 days of avenciguat treatment in Child-Pugh A cirrhosis detected by an oral cholate challenge test

Eric J. Lawitz, Judith Ertle, Corinna Schoelch, Isabella Gashaw, Steve M. Helmke, Gregory T Everson | Liver Transplantation 2024 Jun 12