Liver Testing Through a New Investigative Tool

predict liver drug pharmacokinetics

HepQuant’s innovative, noninvasive tests of liver function and physiology provide patients, investigators, care providers, and payers with a dynamic and comprehensive Picture of Liver Health.
testing hepatic impairment

HepQuant’s innovative, noninvasive tests of liver function and physiology provide patients, investigators, care providers, and payers with a dynamic and comprehensive Picture of Liver Health.
measuring hepatic impairment study

HepQuant’s innovative, noninvasive tests of liver function and physiology provide patients, investigators, care providers, and payers with a dynamic and comprehensive Picture of Liver Health.
predict liver drug pharmacokinetics

HepQuant’s innovative, noninvasive tests of liver function and physiology provide patients, investigators, care providers, and payers with a dynamic and comprehensive Picture of Liver Health.
testing hepatic impairment

HepQuant’s innovative, noninvasive tests of liver function and physiology provide patients, investigators, care providers, and payers with a dynamic and comprehensive Picture of Liver Health.
measuring hepatic impairment study

HepQuant’s innovative, noninvasive tests of liver function and physiology provide patients, investigators, care providers, and payers with a dynamic and comprehensive Picture of Liver Health.

Liver Function Tests

Breaking Through Conventional Thinking About Liver Health Testing

HepQuant is a privately-held, early-stage medical diagnostics company with unique, patented and patent-pending technology for assessing liver function of patients with chronic liver disease. HepQuant technologies, licensed from the University of Colorado Denver (UCD), have been advanced with the intent to profoundly impact the liver disease landscape – including the research, treatment and patient communities – with diagnostic products that are accurate and minimally invasive. 

Through its Investigational Device Exemption (IDE), HepQuant provides liver testing support services to liver research centers and pharmaceutical companies. The HepQuant tests are designed to evaluate the liver regardless of the etiology of the liver disease.

The HepQuant Story | Where We’ve Been, Where We’re Going

Upcoming Events

♦   Digestive Disease Week | May 21 – 24, 2022 | HepQuant abstracts accepted:

  • The HepQuant’s Disease Severity Index (HepQuant DSI™) Outperforms Child-Pugh (CP) Classification in Quantifying Hepatic Impairment for Prediction of Drug Pharmacokinetics (PK) in Chronic Liver Disease
  • The HepQuant Shunt Disease Severity Index (HepQuant DSI™) Can Aid the Decision to Avoid Endoscopic Screening or Surveillance for Varices Needing Treatment (Poster)

♦  EASL International Liver Congress™ 2022 | June 22–26, 2022

♦  The American College of Clinical Pharmacology® (ACCP) Annual Meeting, Sept 25-27th in Bethesda, MD | HepQuant abstract submitted.

Recent Events

♦  40th Annual J.P. Morgan HealthCare Conference | January 10 – 13, 2022 | San Francisco, CA

♦  NASH-TAG Conference | January 6 – 8, 2022

  • Poster Presentation: HMG-CoA Reductase Inhibitors (Statins) and Metformin are Associated With Preservation of Hepatic Function and Less Portal-Systemic Shunting in Advanced Chronic Liver Disease (CLD)

♦  NASH Summit 2021 | November 29-December 2 | Sponsor

  • Oral PresentationHepQuant: Progressing towards a Sensitive and Reliable Endpoint for Treatment Efficacy.  Greg Everson, MD.
    • New Data from Clinical Trials (response to new pharma therapy, reproducibility, progression to decomp in cirrhosis, portal hypertension) 
    • Pivotal Study and Regulatory Progress
    • Anticipated Timelines for Clinical Trial and Commercial Scale-up

♦  AASLD The Liver Meeting | November 12-15

  • Poster: BI 685509 Improves Hepatic Function in Subjects with Child-Pugh A Cirrhosis and a Liver Stiffness Measurement of >15 KPA: Results from the HepQuant SHUNT Test. Lawitz EJ, Ertle J, Schoelch C, Gawshaw I, Helmke SM and Everson GT. – (Poster Presentation at AASLD, The Liver Meeting 2021) {Lawitz et al: Hepatology 2021, Volume 74, Number 1 (Suppl), 1238A-1239A}
  • Poster: The HepQuant SHUNT Test Predicts the Likelihood of Finding Esophageal Varices and Particularly Large Varices at Endoscopy. Shiffman ML, Leise MD, Reddy KR, Hellstern PA, Hassanein T, Qureshi K, Mena E, Smith AD, Kittelson JM, Helmke SM, Everson GT, HepQuant, and SHUNT-V Investigators Group. {Shiffman et al: Hepatology 2021, Volume 74, Number 1 (Suppl), 1264A-1265A}
  • Oral Presentation: Treatment with HMG-CoA Reductase Inhibitors (Statins) is Associated with Preservation of Hepatic Function in Advanced Chronic Liver Disease (CLD): Results from the SHUNT-V Study. Rahimi RS, Lucas KJ, Weinberg EM, Kayali Z, Bhagat VK, Keaveny AP, Mantry PS, Smith AD, Kittelson JM, Helmke SM, Everson GT, and SHUNT-V Investigators Group. {Rahimi et al:  Hepatology 2021, Volume 74, Number 1 (Suppl), 98A-99A}

♦  American Heart Association (AHA) Annual Meeting | November 13-15

  • Oral Presentation: Clinical and Laboratory Correlates of Impaired Cholate Clearance in the Adult Fontan.  Kim YY, Saef J, Everson G, Helmke S, Carducci J, Glatz AC, Partington SL, Ruckdeschel E, Rychik J, Hoteit MA. {Kim et al: Circulation 2021 Volume 144, Suppl_1, A14429} (See Abstract)

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These images and links are for informational purposes only and do not imply that HepQuant has any formal relationships with the organizations, nor do the organizations endorse HepQuant or its liver function tests.